MRC & Asthma UK Centre in Allergic Mechanisms of Asthma

Contact Details

Department of Asthma, Allergy and Respiratory Science

Kings College London

5th Floor, Bermondsey Wing

Guys Hospital

London SE1 9RT

Telephone

020 7955 4967 or 4571

Email

catherine.hawrylowicz@kcl.ac.uk

Profile

The focus of research in my group is on the therapeutic induction of regulatory T cells for the improved treatment of human asthmatic disease, including steroid refractory asthma. Parallel studies are currently investigating the role of vitamin D and other nuclear receptor family members in regulatory T cell induction and maintenance, as well as its broader role in the maintenance of respiratory health.
Major collaborators within the Centre Professor Chris Corrigan (KCL) Professor Clare Lloyd (Imperial College) Professor Andy Bush (Imperial College) Professor Chris Griffiths (QMUL)
Z Urry, E Xystrakis, D.F. Richards, J. McDonald, Z. Sattar, D.J. Cousins, C.J. Corrigan, Z. Brown and C.M. Hawrylowicz. 2009. TLR9 expression is induced on human IL-10 secreting T cells by calctriol and TLR9 agonists abrogate regulatory function. J Clin Invest. 119(2) 387-98
Lloyd CM and Hawrylowicz CM. 2009. Regulatory T cells in asthma. Immunity. 31(3):438-49.
Hawrylowicz C, Ryanna K. 2010. Asthma and allergy: the early beginnings. Nat Med. 16(3):274-5

MRC & Asthma UK Centre in Allergic Mechanisms of Asthma

Last modified: 04 December 2009 11:38