MRC & Asthma UK Centre in Allergic Mechanisms of Asthma

Contact Details

The Randall Division of Cell and Molecular Biophysics

Kings College London

Guys Campus

London SE1 1UL

Telephone

020 7848 6442

Email

hannah.gould@kcl.ac.uk

Profile

Hannah Gould is Professor of Biophysics and is one of the four principal investigators in the Allergy and Asthma Group in the Randall Division of Cell and Molecular Biophysics. Her research is focused on the biology of IgE and the basis of allergic disease. She has a very active group who are working on a diverse range of topics, from “molecules to the bedside”. With Professors Brian Sutton and Jim McDonnell and Dr. Andrew Beavil, she collaborates in studies of the relation of the structure to function of IgE and its receptors Fc epsilon RI and CD23. With clinical collaborators, Profs. Christopher Corrigan, Gideon Lack and Stephen Durham and others in the MRC Centre, she collaborates on problems relating to allergic mechanisms in asthma and rhinitis. With Dr. David Fear in the Division of Asthma , Allergy and Lung Biology, she collaborates on chromatin remodelling in the regulation of IgE synthesis; her main contribution is single cell imaging of class switch recombination by confocal microscopy. Local germinal centre reactions is a passionate interest. She participates in the design and execution of two current clinical trials, one on the efficacy of an anti-IgE in the treatment of non-atopic asthma and the other on IgE immunotherapy of ovarian cancer. She collaborates with scientists in the US, France, and Belgium

MRC & Asthma UK Centre in Allergic Mechanisms of Asthma

Last modified: 04 December 2009 11:38