MRC & Asthma UK Centre in Allergic Mechanisms of Asthma

Contact Details

King's College London

Department of Nephrology and Transplantation

5th floor, Tower Wing

Guy's Hospital

London SE1 9RT

Telephone

020 7188 3053

Email

graham.lord@kcl.ac.uk

Profile

The main focus of my work to date has been in discovering novel biological mechanisms that control the generation and function of T lymphocytes, which are the key effector cells of adaptive immune responses. Insight into the regulation of these responses is critical in order to design rational treatments for human disease where under- or over-activation of adaptive immunity is pathological. The spectrum of human disease where this occurs is wide and includes autoimmunity, infectious disease, malignancy and transplantation. Translation of basic cell biology into representative animal models and the use of primary human cells whenever possible will hopefully allow identification of powerful targets for the treatment of human disease. The clinical orientation of my work has been towards inflammatory renal disease and transplantation, which complements my medical caseload and should enable rapid translation of scientific discovery into direct patient care.

MRC & Asthma UK Centre in Allergic Mechanisms of Asthma

Last modified: 04 December 2009 11:38