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Professor
Frank
Kelly
Contact Details
Pharmaceutical Science Division
150 Stamford Street, Franklin-Wilkins Building
King's College London
London
SE1 9NH
Telephone
:
0207 848 3894
Email
:
0207 848 3894
Profile
Professor Kelly has over 20 years experience in respiratory biology. Initially as a new blood lecturer at the University of Southampton, then as a Reader/Professor and Head of Lung Biology in the Rayne Institute at St Thomas’ Hospital, London before taking up the chair in Environmental Health at King’s College London and becoming Director of the Environmental Research Group (www.erg.kcl.ac.uk).
During this time his work has focused on oxidant/antioxidant imbalances in a number of patient groups including preterm babies, asthmatics, lung transplant recipients and cystic fibrosis patients. For the last 10 years he has addressed the mechanisms underlying air pollution related lung injury focusing on events occurring within the respiratory tract lining fluid (RTLF) compartment of the lung. He has proposed that oxidant/antioxidant events occurring in RTLF are pivotal to understanding the impact of air pollution on the lung and has employed this knowledge to develop a model system to access the oxidative potential of ambient particulate matter.
He has participated in a number of EU projects, coordinated a MRC Cooperative Group investigating the mechanistic basis of particulate air pollution toxicity and is Deputy Director of the new MRC-HPA Centre for Environment and Health. He has led two major Health Effects Institute (HEI) projects, which examined the potential health benefits of the Congestion Charging Scheme (CCS) and Low Emission Zone (LEZ) in London.
The work programme outlined above has led to over 240 publications in peer-reviewed Journals, 12 contributions to edited works, one book on methodology and most recently a Annals of the New York Academy of Sciences. In addition, over 400 abstracts have arisen, largely through conference participation. Research within the Professor Kelly’s Group has led to a ‘unified theory’ of oxidative stress to explain the underlying mechanism(s) by which air pollutants such as ozone, nitrogen dioxide and particles affect public health.
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Last modified:
04 December 2009 11:38